General and applied entomology are the focus of this collection. Additional subjects include parasitology, medical entomology, ecology, zoological nomenclature and allied orders of arthropods. The library also has rare books, a collection of departmental theses and a significant number of reprints.

The Comstock Memorial Library of Entomology was established in 1914, when the students of John Henry Comstock created a book fund in his honor. Later, Professor Comstock made a personal contribution to the fund and donated his own books to the Library.

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